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Filamentous Influenza Viruses

Identifieur interne : 000454 ( Main/Exploration ); précédent : 000453; suivant : 000455

Filamentous Influenza Viruses

Auteurs : Bernadeta Dadonaite [Royaume-Uni] ; Swetha Vijayakrishnan [Royaume-Uni] ; Ervin Fodor [Royaume-Uni] ; David Bhella [Royaume-Uni] ; Edward C. Hutchinson [Royaume-Uni]

Source :

RBID : PMC:5935222

Abstract

Clinical isolates of influenza virus produce pleomorphic virus particles, including extremely long filamentous virions. In contrast, strains of influenza that have adapted to laboratory growth typically produce only spherical virions. As a result, the filamentous phenotype has been overlooked in most influenza virus research. Recent advances in imaging and improved animal models have highlighted the distinct structure and functional relevance of filamentous virions. In this review we summarise what is currently known about these strikingly elongated virus particles and discuss their possible roles in clinical infections.


Url:
DOI: 10.1099/jgv.0.000535
PubMed: 27365089
PubMed Central: 5935222


Affiliations:


Links toward previous steps (curation, corpus...)


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